Opioid Induced Constipation
Lifetree Clinical Research is currently testing investigational treatments that are being developed for opioid constipation and other manifestations of bowel dysfunction in patients receiving prescription opioids for pain.
The goal of this investigational treatment for opioid constipation is to reduce constipation while preserving the effects of opioid therapy. Constipation is the hallmark of this syndrome. However, this investigational treatment may also help opioid induced bowel dysfunction, a condition that may also include other symptoms like bloating, abdominal cramping and gastroesophageal reflux.
Statistics
In the United States, patients with a variety of underlying conditions receive a total of approximately 1.2 billion days of opioid therapy for pain that is treated for at least 15 days. A few examples of opioid medications are lortab, percocet and oxycontin another word for opioids is narcotics. Fifteen to 90% of patients receiving opioids develop constipation. Current treatment for opioid induced constipation, which includes laxatives, stool softeners and if necessary, reflex evacuation via enema – is distinctly sub-optimal with up to 46% of patients not achieving the desired treatment outcome.
Join our Research Study
If you are between the ages of 18 and 70, suffering from constipation from opioids, and can stay multiple days in our research facility, then call for a confidential screening at (801) 269-8200. You will receive financial compensation for your participation, and health insurance is not required to participate.




